The Role of Adipose-derived Medicinal Signaling Cells In Reconstructive Surgery
The use of medicinal signaling cells in regenerative medicine is not new, especially to treat tissue defects or injury. However, the advancement of technique for harvesting and refining adipose tissue (fat tissue) has unlocked revolutionary new applications for medicinal signaling cells derived from fat. Autologous fat transfer can be utilized in reconstructive surgery as a minimally invasive way of delivering tissue engineering therapy.
Analogous Fat Transfer Explained
The process of removing fat tissue from one part of the body and injecting it into another part is called autologous fat transfer. This procedure has been used for decades in cosmetic and plastic surgery. This minimally invasive technique uses the body’s own cells, reducing the risks of complications due to immunogenicity. For people who are especially wary of artificial fillers, autologous fat transfer is an attractive solution for body contouring or other aesthetic procedure.
Why Use Adipose-Derived Medicinal Signaling Cells?
Medicinal signaling cells are unique in that they can stimulate tissue engineering through stimulation of your body’s own regenerative capabilities and to provide a cushion. Considered one of the best natural healing agents in existence, medicinal signaling cells therapy plays a role in a multitude of musculoskeletal applications. Many people are interested in Stem Cell therapy but are leary of it. Due to ethical concerns of harvesting embryonic stem cells, scientists have found ways to use adult stem cells (mesenchymal cells) instead. Adult stem cells exist in tissues like bone marrow and fat. The FDA however has ruled that adipose derived cells have limited capacity to turn into different types of cells. Adipose tissue however does provide volume and cushioning. They are also felt to have endocrine functions, including acting as medicinal signaling cell. Many studies show that adipose derived medicinal signaling cells do provide benefit for many orthopedic conditions like degenerative joint disease (DJD), tendinopathies, rotator cuff injuries, and degenerative disc disease (DDDz).
In addition, challenges exist for harvesting of bone marrow derived adult stem cells. Retrieval from bone marrow is invasive, and harvesting stem cells can be inconsistent. And while liposuction is a common method of fat retrieval, historically it also damages the cells in the process beyond viability. That is, until the BeautiFILL came to market. With this system, we are able to harvest fat cells with a 95% viability rate. Fat cells remain intact to offer medicinal signaling cell therapy and volume enhancement once injected. As a result, adipose-derived stem cells (ASCs) benefit a variety of musculoskeletal, plastic, cosmetic, and reconstructive surgery procedures.
Benefits of ASCs In Reconstructive Surgery
Using ASCs in reconstructive surgery offers a unique approach to soft tissue repair, utilizing the body’s own healing power. Plus, we can conveniently harvest these cells in an outpatient procedure. ASCs demonstrate benefits when used in treating osteoarthritis, soft tissue injury, trauma, non-healing wounds, and signs of aging. More and more, doctors appreciate the application of adipose-derived signaling cells in tissue engineering because of the biocompatibility and low risk of side effects. With the enhanced healing ability of the medicinal signaling cells, patients see improved outcomes.