317 St. Francis Dr. Suite 350
Greenville, SC 29601


317 St. Francis Dr.
Suite 350
Greenville, SC 29601
Tel: 1-864-235-1834, Fax: 1-864-235-2486

Call us Today for an Appointment

864-235-1834

Adipose vs. Bone Marrow or Placental Derived Cellular Therapy

laboratory cells

An effective and common procedure that we offer at Piedmont Physical Medicine & Rehabilitation is cell therapy for tissue engineering. This treatment is typically brought to the attention of patients with degenerative arthritis, musculoskeletal disorders, or peripheral arterial related disease. However, not all cell therapy grafts are identical. At our clinic,  medicinal signaling cells are derived from adipose (Mesenchyme) tissue to facilitate your body’s own natural healing response, and to provide support, volume enhancement and cushioning.

The procedure for harvesting autologous stem cells (stem cells from the patient’s own body), such as adipose and bone marrow-derived stem cells, is performed as an outpatient procedure with little to no downtime. It is also generally not overly painful.

Once the cells have been harvested, they are they can be injected, or grafted, into the arthritic or musculoskeletal injury site. This stimulates tissue repair and ultimately reduces or eliminates pain. As no harvesting is required with placental-derived products,  they are easier to use but these products also are not autologus (from your own body) and less robust in their abilities.  Let’s look closer into each type of therapy and see how they share similarities or differ:

 

Adipose Derived Medicinal Signalling Cells

  • Adipose/fat tissue is a great source of medicinal signaling cells and growth factors for patients of all ages
  • These cells are harvested from adipose tissue (fat) via liposuction
  • Donor sites frequently include the abdominal wall, the buttock (below the iliac crest), and the love handles (above the iliac crest) – a local anesthetic is used for this procedure
  • Adipose derived stem cells are among the most common type to harvest
  • The body’s response time is typically within 21 days; we call this the “Eureka Day”
  • Platelet rich plasma (PRP) injections are always needed for this type of cell therapy – the PRP initiates a wound healing response

 

Bone Marrow Derived Cells

  • Bone marrow is a great source of stem cells and growth factors for patients 45 or younger (preferably 40 or younger)
  • The donor site is usually the iliac crest (pelvis), performed with a specialized type of needle, with an approach from either front or back – local anesthetic is used
  • The procedure (numbing, tracing, and the extraction) takes about 1-2 hours
  • The body’s response time is typically within 21 days; we call this the “Eureka Day”
  • Platelet rich plasma (PRP) injections are always needed for this type of stem cell therapy – the PRP initiates a wound healing response

 

Placental Derived Cell Products

  • Placental derived cell products can be given to any patient (patient-rejection is extremely rare) and no surgery is required to harvest cells (that makes your life much easier!)
  • Third parties harvest these cell products from the amniotic sac – not an embryo!
  • It is safe and ethical, does not interfere with any moral or religious beliefs, and obtained after giving birth
  • It is monitored and processed at an FDA approved biologic lab before it is delivered to the clinic
  • Placental-derived cell products require careful and diligent planning because they have an extremely short shelf life once prepared for grafting – only 10 minutes! A physician who is experienced in grafting is required
  • Often platelet rich plasma (PRP) injections are not necessary at the time of the graft (so that’s a money-saver) however, if the patient’s body does not respond, then we can always jump start the graft by performing a PRP graph 2 weeks later

 

As you can see, each cell therapy type has its own unique qualities. The best choice regarding what option to use is completely dependent on the condition, the patient, and the practitioner.  After all, we want to make the right decision together. Give us a call at 864 235 1834; let’s figure out the right solution for your chronic pain condition.