317 St. Francis Dr. Suite 350
Greenville, SC 29601


317 St. Francis Dr.
Suite 350
Greenville, SC 29601
Tel: 1-864-235-1834, Fax: 1-864-235-2486

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864-235-1834

Adipose vs. Bone Marrow or Placental Derived Stem Cells

laboratory cells

An effective and common procedure that we offer at Piedmont Physical Medicine & Rehabilitation is Stem Cell Regenerative Therapy. This treatment is typically brought to the attention of patients with degenerative arthritis, musculoskeletal disorders, or peripheral arterial related disease. However, not all stem cell therapy transplants are identical. At our clinic, stem cells are derived from adipose (Mesenchyme) tissue, bone marrow, or placental tissue (from the amniotic sac).

The procedure for harvesting autologous stem cells (stem cells from the patient’s own body), such as adipose and bone marrow-derived stem cells, is performed as an outpatient procedure with little to no downtime. It is also generally not overly painful.

Once the cells have been harvested, they are concentrated in a centrifuge so that they can be injected, or grafted, into the arthritic or musculoskeletal injury site. This stimulates tissue repair and ultimately reduces or eliminates pain. The process is much easier with placental-derived stem cells, as no harvesting is required. But let’s look closer into each type of stem cell and see how they share similarities or differ:

 

Adipose Derived Stem Cells

  • Adipose/fat tissue is a great source of stem cells and growth factors for patients of all ages
  • Stem cells are harvested from adipose tissue (fat) via liposuction
  • Donor sites frequently include the abdominal wall, the buttock (below the iliac crest), and the love handles (above the iliac crest) – a local anesthetic is used for this procedure
  • Adipose derived stem cells are among the most common type to harvest
  • The body’s response time is typically within 21 days; we call this the “Eureka Day”
  • Platelet rich plasma (PRP) injections are always needed for this type of stem cell therapy – the PRP initiates a wound healing response

 

Bone Marrow Derived Stem Cells

  • Bone marrow is a great source of stem cells and growth factors for patients 45 or younger (preferably 40 or younger)
  • The donor site is usually the iliac crest (pelvis), performed with a specialized type of needle, with an approach from either front or back – local anesthetic is used
  • The procedure (numbing, tracing, and the extraction) takes about 1-2 hours
  • The body’s response time is typically within 21 days; we call this the “Eureka Day”
  • Platelet rich plasma (PRP) injections are always needed for this type of stem cell therapy – the PRP initiates a wound healing response

 

Placental Derived Stem Cells

  • Placental derived stem cells can be given to any patient (patient-rejection is extremely rare) and no surgery is required to harvest cells (that makes your life much easier!)
  • Stem cells are harvested from an amniotic sac – not an embryo!
  • It is safe and ethical, does not interfere with any moral or religious beliefs, and obtained after giving birth
  • It is monitored and processed at an FDA approved biologic lab before it is delivered to our clinic
  • Placental-derived stem cells require careful and diligent planning because they have an extremely short shelf life once prepared for grafting – only 10 minutes! A physician who is experienced in grafting is required
  • Often platelet rich plasma (PRP) injections are not necessary at the time of the graft (so that’s a money-saver) however, if the patient’s body does not respond, then we can always jump start the graft by performing a PRP graph 2 weeks later

 

As you can see, each stem cell type has its own unique qualities. The stem cells a patient receives is completely dependent on the condition, the patient, and the practitioner. Generally speaking, the older you are the fewer stem cells you have, so it might be more appealing to use placental derived stem cells in cases such as these. But, at the end of the day, we want to make the right decision together. Give us a call at 864 235 1834; let’s figure out the right solution for your chronic pain condition.